Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196060 | 0.93 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL9463999 | 0.86 | LMNA (0.46) | MTNR1AMTNR1BLMNAMAPTALOX15 | |
| SCHEMBL896992 | 0.81 | ALDH1A1 (0.53) | MTNR1AMTNR1BLMNAMAPTALDH1A1 | |
| SCHEMBL6360882 | 0.81 | AR (0.61) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL9464178 | 0.80 | PPARG (0.44) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL3364884 | 0.80 | POLB (0.60) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL295187 | 0.79 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1TDP1 | |
| SCHEMBL3413225 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TDP1 | |
| SCHEMBL7270606 | 0.78 | LMNA (0.50) | MTNR1AMTNR1BLMNA | |
| SCHEMBL9464184 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |