Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464093 | 0.86 | MTNR1A (0.50) | LMNAMTNR1AMTNR1BTDP1MAPT | |
| SCHEMBL805314 | 0.81 | HTT (0.51) | LMNAMTNR1AMTNR1BHTTTDP1 | |
| SCHEMBL9196060 | 0.80 | MTNR1A (0.48) | LMNAMTNR1AMTNR1BMAPT | |
| SCHEMBL805315 | 0.79 | MEN1 (0.52) | LMNAMAPT | |
| SCHEMBL9463439 | 0.79 | ALDH1A1 (0.44) | TDP1 | |
| SCHEMBL6378681 | 0.77 | SLC1A1 (0.42) | TDP1 | |
| SCHEMBL7270606 | 0.76 | LMNA (0.50) | LMNAMTNR1AMTNR1B | |
| SCHEMBL868517 | 0.76 | THRB (0.59) | LMNAMTNR1AMTNR1BHTTTDP1 | |
| SCHEMBL8447408 | 0.75 | ALDH1A1 (0.40) | LMNAMAPT | |
| SCHEMBL25282287 | 0.75 | THRB (0.57) | LMNAMTNR1AMTNR1BHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |