Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277376 | 0.74 | GAA (0.49) | ACHENPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL12075725 | 0.73 | ALDH1A1 (0.66) | ACHENPC1ALDH1A1KDM4EHPGD | |
| Marmesin SCHEMBL29471037 | 0.72 | ACHE (1.00) | ACHENPC1ALDH1A1KDM4EHPGD | |
| Marmesin SCHEMBL546574 | 0.72 | ACHE (1.00) | ACHENPC1ALDH1A1KDM4EHPGD | |
| Marmesin SCHEMBL12062107 | 0.72 | ACHE (1.00) | ACHENPC1ALDH1A1KDM4EHPGD | |
| Marmesin SCHEMBL30977125 | 0.72 | ACHE (1.00) | ACHENPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL31708310 | 0.72 | GAA (0.47) | ACHENPC1ALDH1A1KDM4EHPGD | |
| Dihydroxanthyletin SCHEMBL4741095 | 0.71 | GAA (0.60) | ACHENPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL14466187 | 0.71 | GAA (0.60) | ACHENPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL23940440 | 0.70 | TDP1 (0.38) | NPC1RAB9ACA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216176-A | 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor | LEHIGH UNIVERSITY (US) | 1993-06-01 | — | — | US | disclosed |