Marmesin

Marmesin

SCHEMBL546574

CC(C)(O)C1Cc2cc3ccc(=O)oc3cc2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 3/20 1.00
▸ NPC1 O15118 1/20 1.00
▸ ALDH1A1 P00352 5/20 0.79
▸ HPGD P15428 5/20 0.79
▸ GAA P10253 5/20 0.79
▸ KDM4E B2RXH2 4/20 0.79
▸ HSD17B10 Q99714 1/20 0.74
▸ L3MBTL1 Q9Y468 2/20 0.67
▸ LMNA P02545 1/20 0.63
▸ RAB9A P51151 1/20 0.63
▸ HIF1A Q16665 10/20 0.60
▸ GAPDH P04406 1/20 0.59
▸ MGAM O43451 1/20 0.57
▸ SI P14410 1/20 0.57
▸ PTPN1 P18031 1/20 0.57
▸ MGAM2 Q2M2H8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Marmesin SCHEMBL30977125 1.00 ACHE (1.00) ACHENPC1ALDH1A1HPGDGAA
Marmesin SCHEMBL12062107 1.00 ACHE (1.00) ACHENPC1ALDH1A1HPGDGAA
Marmesin SCHEMBL29471037 1.00 ACHE (1.00) ACHENPC1ALDH1A1HPGDGAA
Marmesin SCHEMBL503874 0.93 ACHE (0.86) ACHENPC1ALDH1A1HPGDGAA
Marmesin Acetate SCHEMBL2257271 0.85 ALDH1A1 (1.00) ACHENPC1ALDH1A1HPGDGAA
Marmesin Acetate SCHEMBL12062110 0.85 ALDH1A1 (1.00) ACHENPC1ALDH1A1HPGDGAA
Felamidin SCHEMBL30467160 0.81 ALDH1A1 (0.75) ACHENPC1ALDH1A1HPGDGAA
(-)-Prantschimgin SCHEMBL13337338 0.81 ALDH1A1 (0.78) ACHENPC1ALDH1A1HPGDGAA
Felamidin SCHEMBL12062114 0.81 ALDH1A1 (0.75) ACHENPC1ALDH1A1HPGDGAA
SCHEMBL30777266 0.78 ALDH1A1 (0.71) ACHENPC1ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
US-20250213633-A1 PHARMACEUTICAL COMPOSITIONS ABDELWAHAB HISHAM HASSAN (AE) 2025-07-03 — — US claimed
CN-119215104-A Traditional Chinese medicine extract and application thereof in preparation of cell necrotic apoptosis inhibitor 河南中医药大学 2024-12-31 — — CN claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
WO-2024134655-A1 CITRUS PLANTS WITH MODIFIED PRODUCTION OF COUMARINS AND FURANOCOUMARINS METHODS OF PRODUCING SAME AND PRODUCTS OBTAINED THEREBY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (IL) 2024-06-27 — — WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
CN-106674240-B The isolation and purification method of alicyclic monomer in a kind of different RADIX PEUCEDANI 成都普思生物科技股份有限公司 2019-03-29 — — CN claimed
CN-106727786-A A kind of antipyretic of children's Integrated TCM and preparation method thereof 郑州郑先医药科技有限公司 2017-05-31 — — CN claimed
CN-106727642-A A kind of children's antipyretic 郑州郑先医药科技有限公司 2017-05-31 — — CN claimed
US-20120277297-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2012-11-01 — — US claimed
EP-2001463-A1 A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS Council of Scientific and Industrial Research (IN) 2008-12-17 — — EP claimed
US-20080009544-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-01-10 — — US claimed
WO-2007107846-A1 A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-09-27 — — WO claimed
CN-1163760-A Health food containing active component of Tianshishan ginseng and Chinese angelica plant DONG FAMING (CN) 1997-11-05 — — CN claimed
EP-4649826-A1 BIRD DAMAGE-PREVENTING COMPOSITION Hanbio Co., Ltd (KR) 2025-11-19 — — EP disclosed
US-20250320469-A1 FUSION PROTEIN AND USE FOR BIOCONVERTING MOLECULES UNIV DE LORRAINE (FR) 2025-10-16 — — US disclosed
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS IMPELLO BIOSCIENCES, INC. 2025-10-09 — — US disclosed
WO-2001049306-A1 BALANITES AEGYPTIACA EXTRACTS FOR TREATMENT OF HIV/AIDS AND LEUKEMIA HAMID OSMAN A MONIEUM (SD) 2001-07-12 — — WO disclosed
CN-1163760-A Health food containing active component of Tianshishan ginseng and Chinese angelica plant DONG FAMING (CN) 1997-11-05 — — CN disclosed
WO-1997023234-A1 BALANITES AEGYPTIACA METHOD OF TREATMENT NATIONAL RESEARCH COUNCIL (SD) 1997-07-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009544-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors ACHE, BCHE, CHRNB1 ACHE 1/4885NPC1 671/4885ALDH1A1 1025/4885
US-20250311723-A1 METHODS AND COMPOSITIONS FOR ALTERING SECONDARY METABOLITES IN PLANTS ERG28, AHCY, BROX ACHE 2895/4885NPC1 2260/4885ALDH1A1 4108/4885
US-20250320469-A1 FUSION PROTEIN AND USE FOR BIOCONVERTING MOLECULES BLVRB, POR, CBR3 ACHE 3779/4885NPC1 2299/4885ALDH1A1 2325/4885
US-20120277297-A1 Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors ACHE, BCHE, CYP3A7 ACHE 1/4885NPC1 1194/4885ALDH1A1 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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