Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33659 | 0.85 | MAPT (0.46) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL15928730 | 0.84 | ALDH1A1 (0.48) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL5707664 | 0.81 | PDE10A (0.45) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL21648272 | 0.80 | ALDH1A1 (0.48) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL11474256 | 0.80 | GAA (0.48) | TSHRALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9398331 | 0.77 | RAD52 (0.45) | TSHRALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL12065127 | 0.75 | ALDH1A1 (0.52) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL22778507 | 0.75 | ALDH1A1 (0.52) | CASP1TSHRALDH1A1CYP3A4PDE10A | |
| SCHEMBL9520267 | 0.75 | ALDH1A1 (0.37) | CASP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL693139 | 0.74 | CASP1 (0.61) | CASP1TSHRALDH1A1CYP3A4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5230710-A | SUBSTITUTED 2,6-DIAMINOTOLUENES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS FOR KERATINIC FIBERS COMPRISING THESE COMPOUNDS | HANS SCHWARZKOPF GMBH (DE) | 1993-07-27 | — | — | US | disclosed |
| US-4196145-A | OXIDATION COLOR DYES | CLAIROL INCORPORATED (US) | 1980-04-01 | — | — | US | disclosed |
| US-4092102-A | HAIR DYES, OXIDATION DYES | CLAIROL INCORPORATED (US) | 1978-05-30 | — | — | US | disclosed |