Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671472 | 0.85 | SRD5A2 (0.46) | MAPTL3MBTL1MAPK1TDP1HPGD | |
| SCHEMBL9670636 | 0.82 | L3MBTL1 (0.42) | LMNAALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL9464583 | 0.79 | NOTUM (0.56) | LMNANOTUMALDH1A1GABRA1GABRG2 | |
| SCHEMBL2229747 | 0.79 | NOTUM (0.66) | LMNANOTUMALDH1A1GABRA2GABRB2 | |
| SCHEMBL1880494 | 0.74 | NOTUM (0.63) | LMNANOTUMALDH1A1GABRA1GABRG2 | |
| SCHEMBL1878934 | 0.74 | NOTUM (0.63) | NOTUMALDH1A1GABRA2GABRB2MAPT | |
| SCHEMBL9248509 | 0.74 | LMNA (0.60) | LMNANOTUMALDH1A1GABRA2GABRB2 | |
| SCHEMBL11070583 | 0.74 | KDM4E (0.52) | LMNAALDH1A1GABRA2GABRB2PPIA | |
| SCHEMBL9464564 | 0.73 | NOTUM (0.66) | NOTUMALDH1A1GABRA2GABRB2MAPT | |
| Hydrochloric Acid SCHEMBL1878932 | 0.73 | NOTUM (0.62) | NOTUMALDH1A1GABRA2GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179111-A | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | claimed |
| EP-0323799-B1 | IMIDAZOLE DERIVATIVES II | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |
| US-5179111-A | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | disclosed |