Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464425 | 0.85 | LMNA (0.49) | PTGER1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL4422234 | 0.78 | P4HTM (0.56) | SRD5A2P4HTMMRGPRX4MEN1KMT2A | |
| SCHEMBL9670636 | 0.76 | L3MBTL1 (0.42) | PTGER1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL9671368 | 0.73 | KDM4E (0.55) | KDM4EP4HTMTDP1L3MBTL1MEN1 | |
| SCHEMBL2820469 | 0.72 | BRD4 (0.66) | SRD5A2P4HTMPTGER1HPGDRXRA | |
| SCHEMBL69486 | 0.71 | KDM4E (0.55) | KDM4EP4HTML3MBTL1 | |
| SCHEMBL8204822 | 0.71 | FOLH1 (0.69) | SRD5A2FOLH1PTGER1MAPTMAPK1 | |
| SCHEMBL17799483 | 0.70 | SGMS2 (0.64) | KDM4EFOLH1PTGER1MAPTL3MBTL1 | |
| SCHEMBL27894425 | 0.70 | KDM4E (0.54) | KDM4EP4HTML3MBTL1 | |
| SCHEMBL6591502 | 0.69 | HDAC3 (0.61) | KDM4EP4HTMPTGER1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323799-B1 | IMIDAZOLE DERIVATIVES II | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |