Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464598 | 0.95 | SMN1; SMN2 (0.46) | AVPR1BADORA2AADORA1MAPTKMT2A | |
| SCHEMBL9465249 | 0.94 | MAPT (0.49) | AVPR1BADORA2AADORA1MAPTKMT2A | |
| SCHEMBL9465734 | 0.92 | ADRA1A (0.48) | AVPR1BMAPTKMT2AADRA1AHRH1 | |
| SCHEMBL9465027 | 0.90 | MAPT (0.54) | ADORA2AMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL9465687 | 0.90 | SMN1; SMN2 (0.50) | AVPR1BMAPTKMT2AMEN1LMNA | |
| SCHEMBL9465745 | 0.89 | SLC2A1 (0.47) | AVPR1BMAPTKMT2AMEN1TSHR | |
| SCHEMBL9465008 | 0.89 | MAPT (0.47) | AVPR1BMAPTKMT2AADRA1AHRH1 | |
| SCHEMBL9464546 | 0.88 | MAPT (0.47) | AVPR1BMAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL9465081 | 0.88 | MAPT (0.45) | AVPR1BMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL9464952 | 0.86 | MAPT (0.46) | AVPR1BMAPTKMT2AADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |