Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465249 | 0.95 | MAPT (0.49) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9464598 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9464655 | 0.90 | AVPR1B (0.47) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9464952 | 0.88 | MAPT (0.46) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9465787 | 0.87 | MAPT (0.45) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9464945 | 0.87 | MAPT (0.45) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL9464810 | 0.86 | SIGMAR1 (0.50) | MAPTLMNAALDH1A1POLBMAPK1 | |
| SCHEMBL9464643 | 0.86 | AVPR1B (0.46) | MAPTKMT2AMEN1LMNAAVPR1B | |
| SCHEMBL9465027 | 0.85 | MAPT (0.54) | SMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL9465008 | 0.84 | MAPT (0.47) | SMN1; SMN2MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |