Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464952 | 0.94 | MAPT (0.46) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9464945 | 0.93 | MAPT (0.45) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9465787 | 0.93 | MAPT (0.45) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9464655 | 0.92 | AVPR1B (0.47) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9464598 | 0.88 | SMN1; SMN2 (0.46) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9464643 | 0.86 | AVPR1B (0.46) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9465249 | 0.86 | MAPT (0.49) | ADRA1AHRH1ADRA1BMAPTMEN1 | |
| SCHEMBL9464810 | 0.84 | SIGMAR1 (0.50) | ADRA1AHRH1MAPTALDH1A1LMNA | |
| SCHEMBL9465687 | 0.82 | SMN1; SMN2 (0.50) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL9465027 | 0.81 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |