Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464945 | 0.99 | MAPT (0.45) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9465787 | 0.99 | MAPT (0.45) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9465734 | 0.94 | ADRA1A (0.48) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9464643 | 0.92 | AVPR1B (0.46) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9465249 | 0.92 | MAPT (0.49) | MAPTADRA1AHRH1ADRA1BMEN1 | |
| SCHEMBL9464810 | 0.90 | SIGMAR1 (0.50) | MAPTADRA1AHRH1ALDH1A1LMNA | |
| SCHEMBL9465687 | 0.88 | SMN1; SMN2 (0.50) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9464655 | 0.86 | AVPR1B (0.47) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9464584 | 0.82 | ADRA1A (0.53) | MAPTADRA1AHRH1ADRA1BALDH1A1 | |
| SCHEMBL9464598 | 0.82 | SMN1; SMN2 (0.46) | MAPTADRA1AHRH1ADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |