SCHEMBL9464693

SCHEMBL9464693

Cc1cc(=O)n(-c2c(C)cccc2Cl)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
MAPT P10636 5/20 0.62
KDM4E B2RXH2 4/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
KMT2A Q03164 6/20 0.45
MEN1 O00255 3/20 0.45
GAA P10253 2/20 0.45
HTT P42858 2/20 0.45
LMNA P02545 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
ALKBH3 Q96Q83 1/20 0.41
ALPL P05186 1/20 0.39
KDM5A P29375 1/20 0.38
KDM2B Q8NHM5 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
POLB P06746 1/20 0.37
GRIA1 P42261 1/20 0.36
CACNG8 Q8WXS5 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10518257 0.83 MAPT (0.57) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11751231 0.81 NOX4 (0.48) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL10952517 0.81 ALKBH5 (0.57) ALDH1A1MAPTKDM4ESMN1; SMN2CTSA
SCHEMBL19322453 0.81 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL11426377 0.80 ALDH1A1 (0.54) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL10359609 0.79 ALDH1A1 (0.45) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL20394527 0.77 ALDH1A1 (0.77) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL4029048 0.77 ALDH1A1 (1.00) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL7454623 0.76 ALDH1A1 (0.56) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A
SCHEMBL4023307 0.73 MAPT (0.57) ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012716-B1 MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS CIBA-GEIGY AG (CH) 1983-06-15 EP claimed
EP-0012716-A1 Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials CIBA-GEIGY AG (CH) 1980-06-25 EP claimed
US-9758486-B1 Edaravone-gossypol derivatives with antitumor activities and a method of preparing the same SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2017-09-12 US disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0267385-B1 ASYMMETRIC 1:2-CHROMIUM COMPLEX DYESTUFFS BAYER AG (DE) 1991-10-09 EP disclosed
EP-0241414-B1 PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES CIBA-GEIGY AG (CH) 1991-05-08 EP disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4990598-A Colorfastness CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK 1991-02-05 US disclosed
EP-0198796-B1 MONOAZO DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-12-05 EP disclosed
US-4918183-A Monoazo dyes, process for their preparation, and the use thereof CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
US-4906740-A Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed
EP-0017768-B1 REACTIVE DYESTUFFS AND THEIR USE BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
US-4234479-A PRINTING AND DYEING NITROGEN-CONTAINING FIBERS; YELLOW BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed
EP-0017768-A1 Reactive dyestuffs and their use BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0012716-A1 Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed
US-4169091-A Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-25 US disclosed
US-4083839-A Unsymmetrical mono sulfo containing 1:2 azo, azo chromium complex dyes CIBA-GEIGY CORPORATION (US) 1978-04-11 US disclosed
US-4029643-A Chromium containing azo dyes NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-06-14 US disclosed
US-3970615-A Unsymmetrical mono-sulfo containing chromium complexes of azo dyes CIBA-GEIGY CORPORATION (US) 1976-07-20 US disclosed