Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464741 | 1.00 | POLB (0.53) | POLBNPC1RAB9AGPR139EGLN1 | |
| SCHEMBL8297129 | 0.83 | POLB (0.56) | POLBNPC1RAB9AGPR139EGLN1 | |
| SCHEMBL34461718 | 0.83 | LMNA (0.51) | POLBEGLN1ALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL21274872 | 0.82 | ALDH1A1 (0.56) | EGLN1ALDH1A1SMN1; SMN2THRBCA1 | |
| SCHEMBL21274871 | 0.82 | ALDH1A1 (0.56) | EGLN1ALDH1A1SMN1; SMN2THRBCA1 | |
| SCHEMBL24571488 | 0.81 | POLB (0.58) | POLBNPC1RAB9AGPR139P2RX7 | |
| SCHEMBL15271936 | 0.81 | POLB (0.58) | POLBNPC1RAB9AGPR139P2RX7 | |
| SCHEMBL5451054 | 0.81 | POLB (0.62) | POLBNPC1RAB9AGPR139P2RX7 | |
| SCHEMBL16235035 | 0.81 | TRPA1 (0.56) | POLBP2RX7ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9464914 | 0.81 | ALDH1A1 (0.52) | POLBNPC1RAB9AGPR139P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |