SCHEMBL9464796

SCHEMBL9464796

CC(C)(C)OC(=O)CC(=O)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 3/20 0.38
DGAT1 O75907 1/20 0.37
CYP2D6 P10635 1/20 0.36
FAAH O00519 8/20 0.35
CES1 P23141 5/20 0.34
CES2 O00748 3/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PLOD2 O00469 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 1/20 0.34
CA7 P43166 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688748 0.90 CA14 (0.35) CA14DGAT1CYP2D6FAAHCES1
SCHEMBL19216586 0.86 DGAT1 (0.37) CA14DGAT1CYP2D6MEN1KMT2A
SCHEMBL6206868 0.81 DGAT1 (0.39) CA14DGAT1CYP2D6MEN1KMT2A
SCHEMBL241533 0.80 DGAT1 (0.46) CA14DGAT1CYP2D6MEN1KMT2A
SCHEMBL197340 0.78 MGAM (0.48) FAAHCES1CES2MEN1CYP1A2
Methyl Alcohol SCHEMBL27995686 0.78 DGAT1 (0.44) CA14DGAT1CYP2D6MEN1KMT2A
SCHEMBL31692035 0.77 PLOD2 (0.34) FAAHCES1CES2MEN1CYP1A2
SCHEMBL12203255 0.76 DGAT1 (0.35) CA14DGAT1CYP2D6MEN1CYP1A2
SCHEMBL18787715 0.76 DGAT1 (0.40) CA14DGAT1CYP2D6MEN1KMT2A
SCHEMBL4466465 0.75 PLOD2 (0.39) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110832110-A Method for producing a metal nanoparticle layer and use thereof in decorative or security elements 巴斯夫欧洲公司 2020-02-21 CN claimed
US-20250234865-A1 Additive Composition for Antifouling Coatings Arxada, LLC 2025-07-24 US disclosed
EP-4402215-A1 ADDITIVE COMPOSITION FOR ANTIFOULING COATINGS Arxada, LLC (US) 2024-07-24 EP disclosed
US-11643561-B2 Process for the preparation of metallic nano-particle layers and their use for decorative or security elements BASF SE 2023-05-09 US disclosed
US-11643561-B2 Process for the preparation of metallic nano-particle layers and their use for decorative or security elements BASF SE 2023-05-09 US disclosed
WO-2023064524-A1 ADDITIVE COMPOSITION FOR ANTIFOULING COATINGS Arxada, LLC (US) 2023-04-20 WO disclosed
US-20230019988-A1 Compositions for Antifouling Protection Arxada Switzerland AG (CH) 2023-01-19 US disclosed
CN-114026181-A Composition for antifouling protection 阿尔萨达股份公司 2022-02-08 CN disclosed
US-20200230646-A1 PROCESS FOR THE PREPARATION OF METALLIC NANO-PARTICLE LAYERS AND THEIR USE FOR DECORATIVE OR SECURITY ELEMENTS BASF SE (DE) 2020-07-23 US disclosed
WO-2020148780-A1 PROCESS FOR PREPARATION OF 4,4,4- TRIFLUOROBUT-2-EN-1-OL AND INTERMEDIATE THEREOF SRF LIMITED (IN) 2020-07-23 WO disclosed
US-20170313696-A1 ISOXAZOLE DERIVATIVE AS MUTANT ISOCITRATE DEHYDROGENASE 1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-11-02 US disclosed
US-20170313696-A1 ISOXAZOLE DERIVATIVE AS MUTANT ISOCITRATE DEHYDROGENASE 1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-11-02 US disclosed
EP-3202766-A1 ISOXAZOLE DERIVATIVE AS MUTATED ISOCITRATE DEHYDROGENASE 1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-08-09 EP disclosed
CN-104109077-B A kind of preparation method of 2,3,3,3-tetrafluoeopropene JIANG University OF TECHNOLOGY (CN) 2015-11-25 CN disclosed
CN-104109077-A A preparing method of 2,3,3,3-tetrafluoropropene UNIV ZHEJIANG TECHNOLOGY 2014-10-22 CN disclosed
US-5252603-A Immunosuppressive analogues and derivatives of succinylacetone CETUS CORPORATION (US) 1993-10-12 US disclosed
US-5216005-A Treating autoimmune diseases, organ tissue transplants CETUS CORPORATION (US) 1993-06-01 US disclosed
US-5173482-A A dioxoalkyl phosponate or a proline-modified polyoxyethylene glycol derivative; autoimmune diseases; organ transplants; immunoassay CETUS CORPORATION (US) 1992-12-22 US disclosed
US-4895872-A TREATING HYPERACTIVE IMMUNE SYSTEMS; AUTOIMMUNE AND GRAFT/HOST DISEASES CETUS CORPORATION (US) 1990-01-23 US disclosed
WO-1990000049-A2 IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE CETUS CORPORATION (US) 1990-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170313696-A1 ISOXAZOLE DERIVATIVE AS MUTANT ISOCITRATE DEHYDROGENASE 1 INHIBITOR IDH1, IDH3A, IDH3B CA14 1823/4885DGAT1 2881/4885CYP2D6 1464/4885
US-20250234865-A1 Additive Composition for Antifouling Coatings PSPH, PHOSPHO1, CFD CA14 206/4885DGAT1 182/4885CYP2D6 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.