Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.46 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464969 | 0.84 | TSHR (0.46) | ALDH1A1GAA | |
| SCHEMBL9465068 | 0.81 | LMNA (0.50) | ADORA2AHSF1ADORA1ALDH1A1KDM4E | |
| SCHEMBL9464694 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDHSD17B10MAPT | |
| SCHEMBL9464977 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9465183 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL9465001 | 0.80 | CYP3A4 (0.46) | ALDH1A1KDM4EGAA | |
| SCHEMBL9465667 | 0.79 | AVPR1B (0.54) | ADORA2AADORA1ALDH1A1HSD17B10 | |
| SCHEMBL9464852 | 0.79 | AVPR1B (0.53) | ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL9464863 | 0.79 | MAPT (0.42) | ADORA2AHSF1ADORA1ADORA3ALDH1A1 | |
| SCHEMBL9465472 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |