Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464977 | 0.89 | ALDH1A1 (0.47) | TSHRALDH1A1KMT2AMEN1AVPR1B | |
| SCHEMBL9465001 | 0.88 | CYP3A4 (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL9464852 | 0.87 | AVPR1B (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1AVPR1B | |
| SCHEMBL9465667 | 0.85 | AVPR1B (0.54) | TSHRALDH1A1SMN1; SMN2AVPR1BTP53 | |
| SCHEMBL9464694 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL9465629 | 0.84 | TLR9 (0.53) | TSHRALDH1A1SMN1; SMN2GAATLR9 | |
| SCHEMBL9464867 | 0.84 | ADORA2A (0.46) | ALDH1A1GAA | |
| SCHEMBL9465183 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL9465472 | 0.83 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL9465068 | 0.82 | LMNA (0.50) | TSHRALDH1A1SMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |