Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL2260480 | 0.85 | LMNA (0.60) | ALDH1A1LMNATHRBCYP3A4CYP2C19 | |
| Tetrahydrofuran SCHEMBL9877354 | 0.85 | LMNA (0.60) | ALDH1A1LMNATHRBCYP3A4CYP2C19 | |
| SCHEMBL6867778 | 0.83 | LMNA (0.57) | ALDH1A1LMNATHRB | |
| SCHEMBL2702135 | 0.83 | LMNA (0.57) | ALDH1A1LMNATHRB | |
| Tetrahydrofuran SCHEMBL10505828 | 0.82 | THRB (0.58) | ALDH1A1LMNATHRB | |
| Tetrahydrofuran SCHEMBL28175157 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNATHRBCYP3A4CYP2C19 | |
| SCHEMBL7802076 | 0.78 | LMNA (0.60) | LMNATHRB | |
| SCHEMBL42798 | 0.78 | — | — | |
| SCHEMBL27476183 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL8081452 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |