Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.35 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464688 | 0.86 | LMNA (0.37) | HTR2CALDH1A1HPGDKDM4EHTT | |
| SCHEMBL9464961 | 0.83 | HTT (0.39) | ALDH1A1KDM4EHTTHSD17B10MEN1 | |
| SCHEMBL9464662 | 0.83 | HTR2C (0.39) | PRKDCPIK3CBPIK3CDHTR2CALDH1A1 | |
| SCHEMBL9465183 | 0.80 | ALDH1A1 (0.43) | PRKDCPIK3CBPIK3CDALDH1A1HPGD | |
| SCHEMBL9464863 | 0.79 | MAPT (0.42) | PRKDCALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9464843 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9465059 | 0.77 | TDP1 (0.39) | PRKDCPIK3CDALDH1A1KDM4EHTT | |
| SCHEMBL9464971 | 0.77 | LIPE (0.45) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL9464999 | 0.77 | ALDH1A1 (0.40) | PRKDCPIK3CBALDH1A1KDM4EHTT | |
| SCHEMBL9465656 | 0.76 | PRKDC (0.42) | PRKDCALDH1A1KDM4EHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |