SCHEMBL6765274

SCHEMBL6765274

C=CCN(C(=O)F)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
ALDH1A1 P00352 5/20 0.44
GLA P06280 2/20 0.44
POLB P06746 2/20 0.44
ESR1 P03372 1/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 2/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10619595 0.85 ALDH1A1 (0.57) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL946547 0.85 TSHR (0.53) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL5932535 0.83 TSHR (0.51) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL327647 0.81 TSHR (0.50) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL8035000 0.81 TSHR (0.50) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL5933109 0.81 TSHR (0.50) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL2577552 0.81 TSHR (0.54) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL5933100 0.81 TSHR (0.50) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL4237587 0.81 TSHR (0.50) TSHRKMT2AMEN1ALDH1A1GLA
SCHEMBL10694643 0.80 TSHR (0.49) TSHRKMT2AMEN1ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10017677-B2 Heat-conductive fluorinated curable composition, cured product thereof, and electric/electronic part SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-10 US disclosed
US-9840601-B2 Method for producing a cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-12 US disclosed
US-20170137583-A1 METHOD FOR PRODUCING A CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-18 US disclosed
US-20170121583-A1 HEAT-CONDUCTIVE FLUORINATED CURABLE COMPOSITION, CURED PRODUCT THEREOF, AND ELECTRIC/ELECTRONIC PART SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-04 US disclosed
US-20160222170-A1 PHOTO-CURABLE FLUOROPOLYETHER-BASED RUBBER COMPOSITION, CURING METHOD THEREOF AND CURED PRODUCT OBTAINED BY THE CURING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-04 US disclosed
US-9221968-B2 Curable perfluoropolyether based gel composition and gel product using cured composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-29 US disclosed
US-20150274960-A1 CURABLE PERFLUOROPOLYETHER BASED GEL COMPOSITION AND GEL PRODUCT USING CURED COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-01 US disclosed
US-9093625-B2 Curable composition for encapsulating optical semiconductor and optical semiconductor apparatus using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-28 US disclosed
US-9023927-B2 Adhesive composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
US-8969451-B2 Method of producing base compound for liquid fluoroelastomer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-03-03 US disclosed
US-20130082300-A1 OPTICAL SEMICONDUCTOR SEALING CURABLE COMPOSITION AND OPTICAL SEMICONDUCTOR APPARATUS USING THIS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-04 US disclosed
US-20120310001-A1 METHOD OF PRODUCING BASE COMPOUND FOR LIQUID FLUOROELASTOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-12-06 US disclosed
US-8299196-B2 Adhesive composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20120123049-A1 THERMOSETTING FLUOROPOLYETHER ADHESIVE COMPOSITION AND ADHESION METHOD SHIN-ETSU CHEMICAL CO., LTD (JP) 2012-05-17 US disclosed
US-20120076532-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-03-29 US disclosed
US-8119760-B2 Curable perfluoropolyether compositions and rubber or gel articles comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-21 US disclosed
US-8110065-B2 Heat-curable fluoropolyether adhesive composition and bonding method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-07 US disclosed
US-20110257315-A1 ADHESIVE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-10-20 US disclosed
US-20110237732-A1 FLUORINE-CONTAINING CURABLE COMPOSITION AND RUBBER ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-09-29 US disclosed
US-20110178263-A1 ADDITION-CURE FLUOROPOLYETHER ADHESIVE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120310001-A1 METHOD OF PRODUCING BASE COMPOUND FOR LIQUID FLUOROELASTOMER PFAS, FLNA, FLNB TSHR 2391/4885KMT2A 126/4885MEN1 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.