Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464952 | 0.92 | MAPT (0.46) | AVPR1BMAPTALDH1A1ADRA1AHRH1 | |
| SCHEMBL9465787 | 0.91 | MAPT (0.45) | AVPR1BMAPTALDH1A1ADRA1AHRH1 | |
| SCHEMBL9464945 | 0.91 | MAPT (0.45) | AVPR1BMAPTALDH1A1ADRA1AHRH1 | |
| SCHEMBL9464810 | 0.90 | SIGMAR1 (0.50) | MAPTALDH1A1ADRA1AHRH1DRD2 | |
| SCHEMBL9465249 | 0.90 | MAPT (0.49) | AVPR1BMAPTADRA1AHRH1ADRA1B | |
| SCHEMBL9465734 | 0.86 | ADRA1A (0.48) | AVPR1BMAPTALDH1A1ADRA1AHRH1 | |
| SCHEMBL9465687 | 0.86 | SMN1; SMN2 (0.50) | AVPR1BMAPTALDH1A1MEN1LMNA | |
| SCHEMBL9464655 | 0.84 | AVPR1B (0.47) | AVPR1BMAPTALDH1A1ADRA1AHRH1 | |
| SCHEMBL9464584 | 0.83 | ADRA1A (0.53) | MAPTALDH1A1ADRA1AHRH1ADRA1B | |
| SCHEMBL9464598 | 0.80 | SMN1; SMN2 (0.46) | AVPR1BMAPTALDH1A1ADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254548-A | Treating dysfunction of cholinergic system | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |