Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075785 | 0.87 | TTK (0.34) | TTKKDM4EALDH1A1L3MBTL1JAK2 | |
| SCHEMBL1076367 | 0.72 | ALDH1A1 (0.33) | TTKKDM4EALDH1A1L3MBTL1JAK2 | |
| SCHEMBL946112 | 0.67 | ALDH1A1 (0.38) | KDM4EALDH1A1L3MBTL1JAK2JAK1 | |
| SCHEMBL946601 | 0.65 | BACE1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL28181585 | 0.60 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1JAK2JAK1 | |
| SCHEMBL13385087 | 0.60 | PDE4B (0.48) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5609138 | 0.58 | PDE4B (0.36) | KDM4EJAK2JAK1TYK2 | |
| SCHEMBL30931031 | 0.57 | KDM4E (0.52) | KDM4EALDH1A1L3MBTL1TSHR | |
| SCHEMBL3296653 | 0.57 | ALDH1A1 (0.48) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28039230 | 0.55 | PDE4B (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |