Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183269 | 0.93 | POLB (0.39) | POLBMEN1LMNAMAPTTSHR | |
| SCHEMBL9181621 | 0.93 | PTGDR2 (0.39) | POLBLMNAMTNR1AMTNR1B | |
| SCHEMBL9176498 | 0.87 | PTGDR2 (0.40) | MEN1MAPTKMT2A | |
| SCHEMBL9183289 | 0.85 | PREP (0.43) | POLBMEN1LMNAMAPTTSHR | |
| SCHEMBL1038532 | 0.84 | HTR2C (0.44) | — | |
| SCHEMBL9175625 | 0.84 | HTR2C (0.44) | — | |
| SCHEMBL9466843 | 0.83 | HTR7 (0.38) | POLBMEN1MAPTTSHRKMT2A | |
| SCHEMBL9467135 | 0.83 | HTR1A (0.51) | LMNA | |
| SCHEMBL9467351 | 0.82 | DRD4 (0.50) | — | |
| SCHEMBL9467334 | 0.82 | DRD4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |