Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.52 |
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483105 | 0.85 | KMT2A (0.56) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL9485291 | 0.85 | KMT2A (0.57) | LMNAKMT2AALDH1A1RAB9APOLB | |
| SCHEMBL10438385 | 0.83 | POLB (0.65) | FLT1FLT4KDRKMT2ATP53 | |
| SCHEMBL14376040 | 0.82 | KDM4E (0.65) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL9484652 | 0.82 | BDKRB1 (0.56) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL29556377 | 0.81 | PCTP (0.58) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL28347229 | 0.81 | PCTP (0.58) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL9468135 | 0.81 | PLK1 (0.54) | FLT1FLT4KDRLMNABDKRB1 | |
| SCHEMBL9468032 | 0.80 | FLT1 (0.58) | FLT1FLT4KDRLMNAKMT2A | |
| SCHEMBL9484328 | 0.80 | BCAT2 (0.57) | FLT1FLT4KDRLMNABDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |