Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375383 | 0.80 | MAPT (0.50) | LIPEALDH1A1PKMNPC1RAB9A | |
| SCHEMBL12233567 | 0.79 | PDK1 (0.51) | PDK1GLRA1USP30ALDH1A1NPC1 | |
| SCHEMBL15551380 | 0.76 | LIPE (0.44) | LIPEALDH1A1PKMHTT | |
| SCHEMBL28019652 | 0.76 | LIPE (0.44) | LIPEALDH1A1PKMHTT | |
| SCHEMBL24518383 | 0.76 | LIPE (0.44) | LIPEALDH1A1PKMHTT | |
| SCHEMBL24511489 | 0.75 | DPP4 (0.41) | LIPEUSP30ALDH1A1PKMSIGMAR1 | |
| SCHEMBL24511675 | 0.75 | DPP4 (0.41) | LIPEUSP30ALDH1A1PKMSIGMAR1 | |
| SCHEMBL24517987 | 0.75 | DPP4 (0.41) | LIPEUSP30ALDH1A1PKMSIGMAR1 | |
| SCHEMBL26817707 | 0.74 | PDK1 (0.50) | PDK1GLRA1USP30RAB9ALMNA | |
| SCHEMBL12233849 | 0.73 | PDK1 (0.49) | PDK1GLRA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218002-A | Morpholinoureas | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | claimed |