Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 4/20 | 0.41 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022491 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRFABP3FABP4FABP5 | |
| SCHEMBL4997683 | 0.77 | TSHR (0.59) | ALDH1A1TSHRHTTHPGDHSD17B10 | |
| SCHEMBL14353864 | 0.77 | PDE4B (0.50) | ALDH1A1ESR2HTTHPGDBCL2L1 | |
| SCHEMBL308199 | 0.75 | CYP2A6 (0.55) | ALDH1A1TSHRFABP3FABP4FABP5 | |
| SCHEMBL355552 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRESR2HTTHPGD | |
| SCHEMBL454643 | 0.75 | PDE4B (0.54) | ALDH1A1ESR2HTTHPGDBCL2L1 | |
| SCHEMBL1754108 | 0.74 | PDE4B (0.52) | ALDH1A1HTTHPGDBCL2L1HSD17B10 | |
| SCHEMBL27588764 | 0.74 | ESR2 (0.52) | ALDH1A1FABP3FABP4FABP5ESR2 | |
| SCHEMBL15509432 | 0.73 | PDE4A (0.43) | ALDH1A1ESR2HTTBCL2L1HDAC4 | |
| SCHEMBL7896869 | 0.72 | TSHR (0.48) | ALDH1A1TSHRFABP3FABP4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243016-A | Improved solubility, polyimides, polyether ketones, polyesters, polyether sulfones | HAY ALLAN S (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5182358-A | Polyetherketones, polyethersulfone, polyetherimides, solubility in organic solvents | HAY ALLAN S (CA) | 1993-01-26 | — | — | US | disclosed |