Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL9469147 | 0.88 | ALDH1A1 (0.59) | ALDH1A1EPHX1GAAKMT2ACYP3A4 | |
| Stearic Acid SCHEMBL9317214 | 0.88 | CES2 (0.51) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL9469601 | 0.85 | ALDH1A1 (0.56) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Behenic Acid SCHEMBL9316970 | 0.85 | CES2 (0.51) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL9317247 | 0.85 | CES2 (0.51) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Succinic Acid SCHEMBL9469556 | 0.85 | ALDH1A1 (0.63) | ALDH1A1EPHX1GAAKMT2ACYP3A4 | |
| Etocarlide SCHEMBL21268036 | 0.80 | MAPT (0.62) | ALDH1A1HTTGAAKMT2AHPGD | |
| Acetic Acid SCHEMBL9470145 | 0.78 | GAA (0.72) | ALDH1A1EPHX1HTTGAAKMT2A | |
| SCHEMBL5131381 | 0.77 | HDAC8 (0.63) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| SCHEMBL282938 | 0.77 | SOAT2 (0.82) | ALDH1A1SOAT2SOAT1ICMTALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |