Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL9317212 | 0.87 | SOAT2 (0.52) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL9469604 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL21838311 | 0.84 | HSD17B10 (0.61) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Behenic Acid SCHEMBL9316968 | 0.84 | SOAT2 (0.52) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL9317244 | 0.84 | SOAT2 (0.52) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Hexanoate SCHEMBL28333349 | 0.84 | SOAT2 (0.57) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL28123864 | 0.83 | SOAT2 (0.57) | ALDH1A1SOAT2SOAT1EPHX1HTT | |
| Palmitic Acid SCHEMBL9330998 | 0.82 | GPR84 (0.61) | ALDH1A1SOAT2SOAT1GPR84PPARG | |
| Diphenylamine SCHEMBL21145188 | 0.82 | GPR84 (0.61) | ALDH1A1SOAT2SOAT1GPR84PPARG | |
| Undecanoate SCHEMBL21145103 | 0.82 | GPR84 (0.61) | ALDH1A1SOAT2SOAT1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236633-A | Blend of transparent polymer, thiourea and copper compounds | JUJO PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |