Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788821 | 0.76 | CDC25B (0.64) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL9470575 | 0.74 | LTA4H (0.44) | ALDH1A1POLBGAALMNA | |
| SCHEMBL9470246 | 0.73 | MAP2K1 (0.47) | ALDH1A1GAA | |
| SCHEMBL9684816 | 0.72 | ALDH1A1 (0.55) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL9469937 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL9469724 | 0.71 | CYP1A2 (0.43) | HSD17B10ALDH1A1GAALMNA | |
| SCHEMBL2058645 | 0.71 | CDC25B (1.00) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL3074652 | 0.71 | CDC25B (1.00) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL5465671 | 0.71 | TDP1 (0.50) | ALDH1A1POLBGAALMNAAPEX1 | |
| SCHEMBL27524893 | 0.71 | AKR1C3 (0.91) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |