Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470575 | 0.83 | LTA4H (0.44) | ALDH1A1GAAHPGD | |
| SCHEMBL9470747 | 0.83 | ATM (0.47) | ALDH1A1HPGD | |
| SCHEMBL9469729 | 0.75 | TOP2A (0.51) | ALDH1A1HPGD | |
| SCHEMBL9368243 | 0.75 | ALDH1A1 (0.53) | MAP2K1ALDH1A1JAK3APPGAA | |
| SCHEMBL9484144 | 0.75 | MAP2K1 (0.48) | MAP2K1ALDH1A1JAK3APPGAA | |
| SCHEMBL29915528 | 0.72 | ALDH1A1 (0.71) | MAP2K1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL1242243 | 0.72 | ALDH1A1 (0.71) | MAP2K1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL5465671 | 0.72 | TDP1 (0.50) | ALDH1A1GAATSHR | |
| SCHEMBL9470718 | 0.72 | ALDH1A1 (0.43) | MAP2K1ALDH1A1JAK3APPGAA | |
| Hydrochloric Acid SCHEMBL27841975 | 0.71 | ALDH1A1 (0.68) | MAP2K1ALDH1A1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |