Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.60 |
| ▸ | BRD4 | O60885 | 8/20 | 0.40 |
| ▸ | BRD2 | P25440 | 8/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.40 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470619 | 0.79 | BRD4 (0.64) | CCKBRBRD4BRD2BRD3 | |
| Formic Acid SCHEMBL9470262 | 0.77 | CCKBR (0.53) | CCKBRBRD4BRD2BRD3CCKAR | |
| SCHEMBL9469852 | 0.75 | CCKBR (1.00) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL9470437 | 0.72 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9645886 | 0.70 | CCKBR (0.73) | CCKBRCCKAR | |
| SCHEMBL9648025 | 0.67 | CCKBR (0.75) | CCKBRBRD4BRD2BRD3CCKAR | |
| SCHEMBL11034765 | 0.67 | OPRK1 (0.55) | CCKBRBRD4BRD2BRD3 | |
| SCHEMBL11734724 | 0.66 | CCKBR (0.56) | CCKBRBRD4BRD2BRD3CCKAR | |
| SCHEMBL9469193 | 0.65 | CCKBR (1.00) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL11638117 | 0.62 | CCKBR (0.45) | CCKBRBRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185331-A | Administering to treat panic and anxiety disorders | MERCK & CO., INC. (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0514125-A1 | Triazolobenzodiazepines | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |