Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761343 | 0.72 | PKM (0.55) | FEN1XDHSMN1; SMN2IDH1HCAR1 | |
| SCHEMBL29693067 | 0.70 | MEN1 (0.53) | FEN1IDH1CALM1GABRA1GABRB2 | |
| SCHEMBL9205683 | 0.69 | HTR1A (0.53) | FEN1MAPT | |
| SCHEMBL7028533 | 0.68 | KDM4E (0.53) | FEN1GABRA1GABRB2GABRB1GABRA3 | |
| Diphenylmethane SCHEMBL10711103 | 0.66 | CALM1 (0.63) | SMN1; SMN2CALM1KMT2AALDH1A1KDM4E | |
| SCHEMBL5761325 | 0.66 | AR (0.61) | — | |
| SCHEMBL17274741 | 0.66 | AHR (0.55) | FEN1IDH1CALM1GABRA1GABRB2 | |
| SCHEMBL10492734 | 0.66 | MEN1 (0.81) | FEN1SMN1; SMN2IDH1CALM1GPR17 | |
| Diphenylmethane SCHEMBL27940463 | 0.65 | CALM1 (0.80) | IDH1CALM1HNF4A | |
| SCHEMBL8094422 | 0.65 | CALM1 (0.92) | IDH1CALM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | disclosed |