SCHEMBL9470357

SCHEMBL9470357

O=C(O)c1cc(OS(=O)(=O)C(F)(F)F)ccc1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.46
EPAS1 Q99814 1/20 0.43
KDM4E B2RXH2 5/20 0.42
POLB P06746 1/20 0.42
CXCR2 P25025 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CXCR1 P25024 1/20 0.40
HTR1A P08908 2/20 0.38
HTR1D P28221 2/20 0.38
HTR1B P28222 2/20 0.38
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 1/20 0.37
TTR P02766 1/20 0.37
PPOX P50336 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPGD P15428 2/20 0.37
CFD P00746 1/20 0.37
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5565709 0.86 ALDH1A1 (0.51) HSD11B1EPAS1KDM4EPOLBCXCR2
SCHEMBL2317318 0.85 RAB9A (0.42) HSD11B1EPAS1KDM4ECA1CA2
SCHEMBL7922665 0.84 CSNK2A1 (0.46) HSD11B1EPAS1KDM4ECA1CA2
SCHEMBL9217908 0.83 STS (0.44) HSD11B1KDM4EPOLBALDH1A1KMT2A
SCHEMBL4705593 0.81 AKR1C3 (0.48) HSD11B1
SCHEMBL3688422 0.80 CA1 (0.44) HSD11B1CXCR2CA1CA2CXCR1
SCHEMBL3491420 0.80 HSD11B1 (0.50) HSD11B1KDM4EPOLBALDH1A1KMT2A
SCHEMBL6551724 0.80 HSD11B1 (0.46) HSD11B1KDM4ECXCR2CA1CA2
SCHEMBL3902735 0.80 HSD11B1 (0.46) HSD11B1KDM4EPOLBCXCR2CA1
SCHEMBL3198514 0.80 ALDH1A1 (0.51) HSD11B1KDM4ECXCR2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5241044-A Soluble poly(p-phenylene)s EDISON POLYMER INNOVATION CORPORATION (US) 1993-08-31 US disclosed