Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19588475 | 0.82 | ADRA1B (0.47) | KEAP1SMN1; SMN2KDM1AHTR1AADRA1B | |
| SCHEMBL1964444 | 0.80 | CHRM2 (0.50) | SMN1; SMN2DRD2HTR1ACHRM2CHRM4 | |
| SCHEMBL5592138 | 0.78 | MEN1 (0.47) | SMN1; SMN2POLB | |
| SCHEMBL888672 | 0.78 | MEN1 (0.50) | SMN1; SMN2DRD2HTR1ACHRM2CHRM4 | |
| SCHEMBL1998867 | 0.78 | KEAP1 (0.71) | KEAP1SMN1; SMN2KDM1ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL5592211 | 0.77 | MEN1 (0.46) | SMN1; SMN2POLB | |
| SCHEMBL1029528 | 0.77 | ADRA1B (0.48) | KEAP1SMN1; SMN2ADRA1DADRA1AADRA1B | |
| Ammonia Solution, Strong SCHEMBL9400430 | 0.76 | KEAP1 (0.68) | KEAP1SMN1; SMN2KDM1ACHRM2CHRM1 | |
| SCHEMBL11222517 | 0.76 | KEAP1 (0.68) | KEAP1SMN1; SMN2KDM1ACHRM2CHRM1 | |
| SCHEMBL3081982 | 0.75 | MEN1 (0.51) | KEAP1SMN1; SMN2KDM1ADRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244591-A | Unsaturated aliphatic carboxylic acids | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1993-09-14 | — | — | US | disclosed |