Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888672 | 0.82 | MEN1 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17525714 | 0.81 | ADRA1B (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9470544 | 0.80 | KEAP1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17525730 | 0.78 | ADRA1B (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6946433 | 0.78 | HRH3 (0.55) | HRH3HRH1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL1961510 | 0.78 | MGLL (0.58) | HRH3HRH1MAPK1SMN1; SMN2 | |
| SCHEMBL13606455 | 0.78 | MGLL (0.58) | HRH3HRH1MAPK1SMN1; SMN2 | |
| SCHEMBL5592224 | 0.77 | MEN1 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11353066 | 0.77 | HRH3 (0.54) | HRH3HRH1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8829446 | 0.77 | FAAH (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426609-B2 | Polymers functionalized with imide compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20110144282-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144282-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | PARG, PIN1, NPEPPS | CHRM2 4095/4885CHRM4 3674/4885CHRM5 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.