Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172070 | 0.96 | CES1 (0.56) | CES1MEN1KMT2ACASP3CASP1 | |
| SCHEMBL9470716 | 0.77 | CES1 (0.56) | CES1MEN1KMT2AHTTMAPT | |
| SCHEMBL9178564 | 0.73 | CASP1 (0.38) | CES1MEN1KMT2ACASP3CASP1 | |
| SCHEMBL749609 | 0.73 | CES1 (0.90) | CES1MEN1KMT2AHTTPOLB | |
| SCHEMBL10367966 | 0.72 | CES1 (0.62) | CES1MEN1KMT2AHTTMAPT | |
| SCHEMBL10367642 | 0.72 | CES1 (0.62) | CES1MEN1KMT2AHTTMAPT | |
| SCHEMBL2429208 | 0.72 | CES1 (0.88) | CES1MEN1KMT2AHTTPOLB | |
| SCHEMBL9170783 | 0.72 | CES1 (0.62) | CES1MEN1KMT2AHTTMAPT | |
| SCHEMBL9178459 | 0.72 | CES1 (0.62) | CES1MEN1KMT2AHTTMAPT | |
| SCHEMBL14074443 | 0.71 | MAPT (0.49) | MEN1KMT2AHTTMAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242912-A | Treatment of autoimmune and rheumatic diseases and osteoporosis | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |