Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CASP4 | P49662 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP9 | P55211 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949919 | 0.77 | POLB (0.42) | CASP1CASP7MAPTMEN1NPC1 | |
| SCHEMBL9170732 | 0.76 | CES1 (0.36) | CASP1CASP7MAPTPIK3CDPIK3CA | |
| SCHEMBL9172070 | 0.74 | CES1 (0.56) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL9172178 | 0.74 | CES1 (0.51) | MAPTMEN1KMT2APOLBCES1 | |
| SCHEMBL9470659 | 0.73 | CES1 (0.51) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL29876689 | 0.69 | MEN1 (0.41) | CASP6MAPTMEN1NPC1RAB9A | |
| SCHEMBL16709616 | 0.68 | ALDH1A1 (0.46) | MAPTMEN1RAB9AKMT2APOLB | |
| SCHEMBL14580057 | 0.68 | ALDH1A1 (0.40) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2060402 | 0.68 | ACHE (0.45) | CASP1CASP3CASP4CASP7CASP9 | |
| SCHEMBL9501575 | 0.68 | PIK3CD (0.49) | CASP1CASP3CASP4CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310096-B1 | Novel cyclic anthranilic acid derivatives and process for their preparation | KYORIN SEIYAKU KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5281600-A | Antiinflammatory agents, rheumatic diseases and immunomodulators | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-01-25 | — | — | US | disclosed |
| US-5147874-A | Antiarthritic agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-4956372-A | ANTIRHEUMATOID AND IMMUNOMODULATORS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |