SCHEMBL947073

SCHEMBL947073

ICCOCCOC1CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5849519 1.00 MEN1 (0.40) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL22787086 0.93 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL22787067 0.93 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL13455405 0.91 MEN1 (0.44) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL6714850 0.91 MEN1 (0.44) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL948840 0.89 MEN1 (0.43) MEN1KMT2AKDM4CL3MBTL1NPC1
Ammonia Solution, Strong SCHEMBL23857767 0.87 MEN1 (0.42) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL22787057 0.86 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL13455407 0.85 MEN1 (0.39) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL23544814 0.82 MEN1 (0.46) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217573-B Vertical monomolecular film field effect control switch and preparation method thereof 南开大学 2024-08-30 CN disclosed
CN-116217573-A Vertical monomolecular film field effect control switch and preparation method thereof 南开大学 2023-06-06 CN disclosed
US-20180009829-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES UNIVERSITY OF OREGON (US) 2018-01-11 US disclosed
US-9771380-B2 Gold nanoparticles and methods of making and using gold nanoparticles UNIVERSITY OF OREGON (US) 2017-09-26 US disclosed
US-9771380-B2 Gold nanoparticles and methods of making and using gold nanoparticles UNIVERSITY OF OREGON (US) 2017-09-26 US disclosed
US-9771380-B2 Gold nanoparticles and methods of making and using gold nanoparticles UNIVERSITY OF OREGON (US) 2017-09-26 US disclosed
EP-2821385-B1 Method for the preparation of therapeutically valuable triphenylbutene derivatives HORMOS MEDICAL LTD (FI) 2016-07-27 EP disclosed
US-20150353580-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES UNIVERSITY OF OREGON 2015-12-10 US disclosed
US-20150353580-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES UNIVERSITY OF OREGON 2015-12-10 US disclosed
US-20150353580-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES UNIVERSITY OF OREGON 2015-12-10 US disclosed
CN-101636372-B Method for the preparation of therapeutically valuable triphenylbutene derivatives HORMOS MEDICAL LTD (FI) 2013-03-27 CN disclosed
EP-2518039-A9 Method for the preparation of therapeutically valuable triphenylbutene derivatives Hormos Medical Ltd. (FI) 2013-02-13 EP disclosed
EP-2518039-A1 Method for the preparation of therapeutically valuable triphenylbutene derivatives Hormos Medical Ltd. (FI) 2012-10-31 EP disclosed
US-8293947-B2 Method for the preparation of therapeutically valuable triphenylbutene derivatives HORMOS MEDICAL LTD. (FI) 2012-10-23 US disclosed
US-20110015448-A1 METHOD FOR THE PREPARATION OF THERAPEUTICALLY VALUABLE TRIPHENYLBUTENE DERIVATIVES HORMOS MEDICAL LTD. 2011-01-20 US disclosed
US-7812197-B2 Alkylation a corresponding alcoholic compound HORMOS MEDICAL LTD. (FI) 2010-10-12 US disclosed
EP-2121553-A1 METHOD FOR THE PREPARATION OF THERAPEUTICALLY VALUABLE TRIPHENYLBUTENE DERIVATIVES Hormos Medical Ltd. (FI) 2009-11-25 EP disclosed
US-20080207956-A1 Alkylation a corresponding alcoholic compound DUCHESNAY INC. (CA) 2008-08-28 US disclosed
WO-2008099059-A1 METHOD FOR THE PREPARATION OF THERAPEUTICALLY VALUABLE TRIPHENYLBUTENE DERIVATIVES HORMOS MEDICAL LTD (FI) 2008-08-21 WO disclosed
WO-2002032963-A1 IMMUNOADJUVANT SYSTEMS ALCHEMIA PTY LTD (AU) 2002-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180009829-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES MPO, SPR, CD63 MEN1 4530/4885KMT2A 2923/4885KDM4C 2892/4885
US-20080207956-A1 Alkylation a corresponding alcoholic compound CYP2E1, PNMT, ADH1A MEN1 2295/4885KMT2A 162/4885KDM4C 236/4885
US-20110015448-A1 METHOD FOR THE PREPARATION OF THERAPEUTICALLY VALUABLE TRIPHENYLBUTENE DERIVATIVES PDGFRB, TPMT, SIRT3 MEN1 2474/4885KMT2A 1897/4885KDM4C 2574/4885
US-20150353580-A1 GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES MPO, SPR, CD63 MEN1 4530/4885KMT2A 2923/4885KDM4C 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.