Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967579 | 1.00 | MEN1 (0.44) | MEN1KMT2ACXCR3OPRM1OPRD1 | |
| SCHEMBL30377560 | 1.00 | MEN1 (0.44) | MEN1KMT2ACXCR3OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL9254983 | 0.98 | MEN1 (0.46) | MEN1KMT2ACXCR3OPRM1OPRD1 | |
| SCHEMBL17647569 | 0.87 | MTNR1A (0.39) | MEN1KMT2ACXCR3PNMTSMYD3 | |
| SCHEMBL29707282 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL32677077 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL29715383 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL1491696 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6866846 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL1491698 | 0.84 | KDM4E (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507275-B1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-11040954-B1 | CXCR3 receptor agonists | RECEPTOS LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC | 2019-11-14 | — | — | US | disclosed |
| WO-2018045246-A1 | CXCR3 RECEPTOR AGONISTS | CELGENE INTERNATIONAL II SARL (CH) | 2018-03-08 | — | — | WO | disclosed |
| CN-1305470-A | Amidine compounds | JAPAN TOBACCO INC (JP) | 2001-07-25 | — | — | CN | disclosed |
| US-5200416-A | CYCLIC AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0018549-B1 | TETRAHYDROISOQUINOLINE COMPOUNDS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Tanabe Seiyaku Co., Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |
| EP-0039804-A1 | Cyclic amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | disclosed |
| US-4294832-A | HYPOTENSIVE AGENTS, ANGIOTENSIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| EP-0018549-A2 | Tetrahydroisoquinoline compounds, process for preparing them and pharmaceutical compositions containing them | Tanabe Seiyaku Co., Ltd. (JP) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040954-B1 | CXCR3 receptor agonists | CXCR3, CXCR1, CCR7 | MEN1 3630/4885KMT2A 3106/4885CXCR3 1/4885 |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | CXCR3, CXCR1, CCR7 | MEN1 3630/4885KMT2A 3106/4885CXCR3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.