SCHEMBL9470985

SCHEMBL9470985

CC(C)(C)C(=O)C(Cl)C(=O)Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.63
GPR55 Q9Y2T6 2/20 0.63
HSP90AA1 P07900 1/20 0.63
ALDH1A1 P00352 7/20 0.47
GAA P10253 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 3/20 0.41
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.40
P2RY1 P47900 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11382683 0.81 MAPT (0.61) MAPTGPR55HSP90AA1ALDH1A1GAA
SCHEMBL9471221 0.79 MAPT (0.62) MAPTGPR55HSP90AA1GAASMN1; SMN2
SCHEMBL11372753 0.78 PDK1 (0.54) MAPTGPR55HSP90AA1MEN1KMT2A
SCHEMBL10681711 0.77 ALDH1A1 (0.50) MAPTALDH1A1GAASMN1; SMN2MEN1
SCHEMBL10698727 0.77 MAPT (1.00) MAPTGPR55HSP90AA1ALDH1A1GAA
SCHEMBL9471936 0.76 MAPT (0.73) MAPTGPR55HSP90AA1ALDH1A1GAA
SCHEMBL13883734 0.76 KMT2A (0.56) MAPTALDH1A1GAASMN1; SMN2MEN1
SCHEMBL14254938 0.76 L3MBTL1 (0.59) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL11380572 0.75 NPC1 (0.60) MAPTGPR55HSP90AA1ALDH1A1GAA
SCHEMBL9471183 0.75 MAPT (0.71) MAPTGPR55HSP90AA1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5266597-A Applying a fungicides EASTMAN KODAK COMPANY (US) 1993-11-30 US claimed
EP-0487154-A1 Fungicidal use of 2-acylacetanilide derivatives EASTMAN KODAK COMPANY (US) 1992-05-27 EP claimed
US-5266597-A Applying a fungicides EASTMAN KODAK COMPANY (US) 1993-11-30 US disclosed
US-5155136-A FUNGICIDAL, 2-ACYLACETANILIDE DERIVATIVES EASTMAN KODAK COMPANY (US) 1992-10-13 US disclosed
EP-0487154-A1 Fungicidal use of 2-acylacetanilide derivatives EASTMAN KODAK COMPANY (US) 1992-05-27 EP disclosed