Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860030 | 0.84 | CA12 (0.60) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9159771 | 0.81 | CA12 (0.57) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9152837 | 0.80 | POLB (0.57) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8860020 | 0.79 | ALDH1A1 (0.55) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9158223 | 0.79 | ALDH1A1 (0.55) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9157740 | 0.77 | KMT2A (0.66) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9471262 | 0.76 | ALDH1A1 (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9471693 | 0.76 | ALDH1A1 (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9157809 | 0.76 | ALDH1A1 (0.62) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9134971 | 0.75 | CA12 (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |