Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157966 | 0.93 | ALDH1A1 (0.58) | KMT2AMEN1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9153787 | 0.92 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9159221 | 0.89 | MEN1 (0.52) | KMT2AMEN1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9152136 | 0.89 | BCHE (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL9158437 | 0.84 | HPGD (0.53) | KMT2AMEN1HPGDMAPK1ALDH1A1 | |
| SCHEMBL9153770 | 0.84 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8860030 | 0.84 | CA12 (0.60) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL9154021 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9152837 | 0.82 | POLB (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL9159771 | 0.81 | CA12 (0.57) | KMT2AMEN1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |