Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153829 | 0.83 | OPRD1 (0.46) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9157740 | 0.82 | KMT2A (0.66) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8860030 | 0.82 | CA12 (0.60) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1414102 | 0.81 | SMN1; SMN2 (0.78) | POLBSMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL9154021 | 0.81 | ALDH1A1 (0.55) | POLBSMN1; SMN2HDAC1HDAC6MEN1 | |
| SCHEMBL9471902 | 0.80 | NPC1 (0.63) | POLBSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9159771 | 0.79 | CA12 (0.57) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9157966 | 0.79 | ALDH1A1 (0.58) | POLBSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9153787 | 0.78 | KMT2A (0.55) | POLBSMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL9158437 | 0.78 | HPGD (0.53) | POLBMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |