Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.75 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472878 | 0.86 | OPRK1 (0.76) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| Medazepam SCHEMBL18472 | 0.86 | OPRK1 (1.00) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| Medazepam SCHEMBL29642025 | 0.86 | OPRK1 (1.00) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| Medazepam SCHEMBL11658148 | 0.86 | OPRK1 (1.00) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| Medazepam SCHEMBL78352 | 0.85 | OPRK1 (0.97) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| SCHEMBL14018729 | 0.83 | OPRK1 (0.84) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| SCHEMBL9473608 | 0.80 | OPRK1 (0.70) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| SCHEMBL9473102 | 0.79 | GABRA1 (0.76) | OPRK1NR1I2ADORA3GABRA1GABRA5 | |
| SCHEMBL11680057 | 0.78 | OPRK1 (0.76) | OPRK1PDE4DNR1I2ADORA3HTR2C | |
| SCHEMBL11682597 | 0.78 | OPRK1 (0.67) | OPRK1PDE4DNR1I2ADORA3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313291-B1 | RADIOACTIVE BENZODIAZEPINE DERIVATIVE AND PROCESSES FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5216147-A | Halogenphenyl benzodiazepine labeled with isotopes iodine or bromine as diagnostic agent for nuclear medicine and has high affinity to benzodiazepine antibodies; short half-life, receptivity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| US-4885152-A | DIAGNOSTIC AGENT FOR NUCLEAR MEDICINE; RADIOPHARMACEUTICAL LABELED WITH RADIOACTIVE IODINE OR BROMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0313291-A1 | Radioactive benzodiazepine derivative and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-26 | — | — | EP | disclosed |