Medazepam

Medazepam

SCHEMBL18472

CN1CCN=C(c2ccccc2)c2cc(Cl)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 8/20 1.00
PDE4D Q08499 2/20 1.00
NR1I2 O75469 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
HTR2C P28335 1/20 1.00
ADRA1A P35348 1/20 1.00
PTGS2 P35354 1/20 1.00
CHRNA4 P43681 1/20 1.00
SLC6A3 Q01959 1/20 1.00
GABRA1 P14867 2/20 0.61
GABRA5 P31644 2/20 0.61
GABRA3 P34903 2/20 0.61
GABRA2 P47869 2/20 0.61
GABRB2 P47870 2/20 0.61
GABRP O00591 1/20 0.61
GABRD O14764 1/20 0.61
CACNA1F O60840 1/20 0.61
ALB P02768 1/20 0.61
GABRB1 P18505 1/20 0.61
GABRG2 P18507 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medazepam SCHEMBL29642025 1.00 OPRK1 (1.00) OPRK1PDE4DNR1I2ADORA3HTR2C
Medazepam SCHEMBL11658148 1.00 OPRK1 (1.00) OPRK1PDE4DNR1I2ADORA3HTR2C
Medazepam SCHEMBL78352 0.99 OPRK1 (0.97) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL14018729 0.92 OPRK1 (0.84) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL9472878 0.86 OPRK1 (0.76) OPRK1PDE4DNR1I2ADORA3HTR2C
Medazepam SCHEMBL30366342 0.86 OPRK1 (0.76) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL11680057 0.86 OPRK1 (0.76) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL9472170 0.86 OPRK1 (0.75) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL3235774 0.84 OPRK1 (0.73) OPRK1PDE4DNR1I2ADORA3HTR2C
SCHEMBL11683117 0.83 OPRK1 (0.71) OPRK1PDE4DNR1I2ADORA3HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7153 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368700-A1 NOVEL PEPTIDE FOR TREATING AN INFECTIOUS DISEASE OR CONDITION OMNIX MEDICAL LTD (IL) 2025-12-04 US claimed
US-20250313597-A1 NOVEL PEPTIDE FOR TREATING AN INFECTIOUS DISEASE OR CONDITION OMNIX MEDICAL LTD. (IL) 2025-10-09 US claimed
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2025-09-04 US claimed
US-20250179064-A1 BENZOQUINOLONE INHIBITORS OF VMAT2 AUSPEX PHARMACEUTICALS LLC 2025-06-05 US claimed
EP-4547696-A1 NOVEL PEPTIDE FOR TREATING AN INFECTIOUS DISEASE OR CONDITION Omnix Medical Ltd. (IL) 2025-05-07 EP claimed
EP-4547697-A1 NOVEL PEPTIDE FOR TREATING AN INFECTIOUS DISEASE OR CONDITION Omnix Medical Ltd. (IL) 2025-05-07 EP claimed
CN-119522109-A Compositions for intermittent administration of calcineurin inhibitors 特雷弗·克利 2025-02-25 CN claimed
CN-119325617-A System and method for assessing disease burden and progression 普罗热尼奇制药公司 2025-01-17 CN claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
EP-4422607-A1 ORAL AND NASAL COMPOSITIONS AND METHODS OF TREATMENT Aquestive Therapeutics, Inc. (US) 2024-09-04 EP claimed
EP-0240904-A2 Process for the preparation of solid pharmaceutical forms BASF Aktiengesellschaft (DE) 1987-10-14 EP claimed
EP-0216555-A2 Use of dioxopiperidine derivatives in the treatment of anxiety, for the reduction of chronic abnormally high brain levels of serotonin or 5-hydroxy-indoleacetic acid, and in the treatment of bacterial or viral infections BTG INTERNATIONAL LIMITED (GB) 1987-04-01 EP claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
EP-0050487-A1 Pharmaceutical compositions comprising a benzodiazepine drug and a phenanthridine derivative PFIZER INC. (US) 1982-04-28 EP claimed
US-4320124-A ANALGESICS PFIZER INC. (US) 1982-03-16 US claimed
US-4316897-A TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1982-02-23 US claimed
EP-0025546-A2 Therapeutical use of tranquillizing benzodiazepine derivatives and mixtures containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-03-25 EP claimed
US-4155904-A Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones SCHERING CORPORATION (US) 1979-05-22 US claimed
US-4044003-A Process for preparing 1,4-benzodiazepines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-23 US claimed
US-4028467-A Analgesic compositions comprising levo-propoxyphene and benzo diazepine and process BERGER FRANK M 1977-06-07 US claimed