Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489089 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1AKT1MEN1 | |
| SCHEMBL10679812 | 0.72 | ALDH1A1 (0.34) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL560335 | 0.71 | AKR1C3 (0.44) | TDP1KMT2ACES2CES1MAPT | |
| SCHEMBL8549786 | 0.70 | MAPT (0.33) | ALDH1A1TDP1MAPK1MAPTTSHR | |
| SCHEMBL11008184 | 0.69 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPK1AKT1MEN1 | |
| SCHEMBL17798412 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPK1MAPTCYP3A4TSHR | |
| SCHEMBL10033941 | 0.66 | RECQL (0.55) | ALDH1A1TDP1MAPK1AKT1MEN1 | |
| SCHEMBL11028515 | 0.66 | RECQL (0.55) | ALDH1A1TDP1MAPK1AKT1MEN1 | |
| SCHEMBL1679834 | 0.65 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1AKT1MEN1 | |
| SCHEMBL301750 | 0.65 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1AKT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192758-A | Antibiotics | MERCK & CO., INC. (US) | 1993-03-09 | — | — | US | disclosed |