SCHEMBL560335

SCHEMBL560335

CC(=C[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
MAPT P10636 2/20 0.41
RXRA P19793 4/20 0.38
RXRB P28702 4/20 0.38
NR4A2 P43354 3/20 0.38
RXRG P48443 3/20 0.38
CYP2C9 P11712 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
APEX1 P27695 8/20 0.35
HTT P42858 1/20 0.34
GLA P06280 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3298614 0.82 AKR1C3 (0.31) AKR1C3MAPT
SCHEMBL5144091 0.77 AKR1C3 (0.50) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL3297070 0.77 AKR1C3 (0.50) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL3293184 0.76 MAPT (0.49) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL3787971 0.76 MAPT (0.49) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL4917439 0.75 AKR1C3 (0.44) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL10679812 0.72 ALDH1A1 (0.34) MAPTKMT2A
SCHEMBL17420014 0.71 AKR1C3 (0.44) AKR1C3MAPTRXRARXRBNR4A2
SCHEMBL9473201 0.71 ALDH1A1 (0.44) MAPTCES2CES1HTTTDP1
SCHEMBL8549786 0.70 MAPT (0.33) MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405530-B1 COATING COMPOSITION FOR SUBSTRATES IMMERSED IN WATER AKZO NOBEL COATINGS INT BV (NL) 2019-10-30 EP claimed
WO-2020158475-A1 (METH)ACRYLIC COPOLYMER, PRESSURE-SENSITIVE ADHESIVE COMPOSITION, PRESSURE-SENSITIVE ADHESIVE, AND PRESSURE-SENSITIVE ADHESIVE SHEET 三菱ケミカル株式会社 2020-08-06 WO disclosed
EP-3543265-A1 (METH)ACRYLIC COPOLYMER, COATING MATERIAL COMPOSITION, COATED ARTICLE AND METHOD FOR FORMING MULTILAYER COATING FILM Mitsubishi Chemical Corporation (JP) 2019-09-25 EP disclosed
US-9624385-B2 Antifouling paint composition, copolymer for antifouling paint composition and method for manufacturing same, and painted object having on surface antifouling paint film formed using said composition NITTO KASEI CO., LTD. (JP) 2017-04-18 US disclosed
US-9309414-B2 Enzyme-based self-polishing coating compositions HEMPEL A/S (DK) 2016-04-12 US disclosed
US-20160068688-A1 ANTIFOULING PAINT COMPOSITION, COPOLYMER FOR ANTIFOULING PAINT COMPOSITION AND METHOD FOR MANUFACTURING SAME, AND PAINTED OBJECT HAVING ON SURFACE ANTIFOULING PAINT FILM FORMED USING SAID COMPOSITION NITTO KASEI CO., LTD. (JP) 2016-03-10 US disclosed
US-20160009925-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM FORMED USING SAID COMPOSITION, AND COATED ARTICLE HAVING ANTIFOULING COATING FILM ON SURFACE NITTO KASEI CO., LTD. (JP) 2016-01-14 US disclosed
US-20140242403-A1 SELF-POLISHING ANTIFOULING PAINT COMPOSITION COMPRISING SOLID PARTICLES OF ENTRAPPED OR ENCAPSULATED ROSIN CONSTITUENTS HEMPEL A/S (DK) 2014-08-28 US disclosed
US-20130195948-A1 Composition DANISCO A/S (DK) 2013-08-01 US disclosed
US-20120031300-A1 ENZYME-BASED SELF-POLISHING COATING COMPOSITIONS HEMPEL A/S (DK) 2012-02-09 US disclosed
US-20100183540-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2010-07-22 US disclosed
US-20050014963-A1 Process for the preparation of organosilylated carboxylate monomers, and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2005-01-20 US disclosed
EP-1476509-A2 SELF-POLISHING ANTIFOULING PAINT Jotun AS (NO) 2004-11-17 EP disclosed
WO-2003070832-A2 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2003-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014963-A1 Process for the preparation of organosilylated carboxylate monomers, and their use in antifouling coatings ACMSD, MMAB, GFER AKR1C3 948/4885MAPT 3107/4885RXRA 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.