Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.73 |
| ▸ | HTR1A | P08908 | 4/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.73 |
| ▸ | DRD3 | P35462 | 9/20 | 0.68 |
| ▸ | DRD4 | P21917 | 4/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9037059 | 0.99 | DRD2 (0.72) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL9467179 | 0.97 | DRD2 (0.69) | DRD2HTR1AHTR2ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL9035124 | 0.96 | DRD2 (0.68) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL9034796 | 0.94 | HTR1A (0.65) | DRD2HTR1AHTR2ADRD4ADRA1A | |
| Hydrochloric Acid SCHEMBL9036734 | 0.93 | HTR1A (0.64) | DRD2HTR1AHTR2ADRD4ADRA1A | |
| SCHEMBL9466381 | 0.84 | DRD2 (0.52) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL9035939 | 0.84 | HTR1A (0.80) | DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL9035828 | 0.84 | DRD2 (0.51) | DRD2HTR1AHTR2ADRD3DRD4 | |
| SCHEMBL9035056 | 0.83 | HTR1A (0.53) | DRD2HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL9466203 | 0.83 | DRD3 (0.66) | DRD2HTR1AHTR2ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225412-A | Antipsychotic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-06 | — | — | US | claimed |