Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617598 | 0.75 | ALDH1A1 (0.52) | LMNAALDH1A1MAPT | |
| SCHEMBL22361321 | 0.74 | TSHR (0.45) | LMNATSHRMEN1KMT2ATDP1 | |
| SCHEMBL51192 | 0.72 | LMNA (0.46) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL3470173 | 0.70 | — | — | |
| SCHEMBL37980 | 0.70 | — | — | |
| SCHEMBL3469333 | 0.69 | — | — | |
| SCHEMBL29590 | 0.67 | — | — | |
| SCHEMBL12225574 | 0.67 | — | — | |
| SCHEMBL25656643 | 0.67 | LMNA (0.42) | LMNATSHRMEN1HPGDBLM | |
| SCHEMBL11762381 | 0.65 | TSHR (0.39) | LMNATSHRMEN1HPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183812-A | Antiviral agent for treating AIDS | NATIONAL INSTITUTES OF HEALTH, THE | 1993-02-02 | — | — | US | disclosed |
| US-5072032-A | Heating trimethyl phosphonoformate, Lawesson's reagent, and solvent to produce trimethyl thiophosphonoformate, hydrolysis of intermediate form thiophosphonoformic acid | NATIONAL INSTITUTES OF HEALTH, THE | 1991-12-10 | — | — | US | disclosed |