SCHEMBL51192

SCHEMBL51192

COP(=O)(CC(=O)O)OC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
TSHR P16473 2/20 0.46
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 2/20 0.38
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.35
USP2 O75604 1/20 0.34
FFAR3 O14843 1/20 0.33
SLC15A2 Q16348 1/20 0.33
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333005 0.80 LDHA (0.35) LMNATSHRMEN1HPGDBLM
SCHEMBL11042103 0.80 POLB (0.34) LMNATSHRPOLB
SCHEMBL5697053 0.79 LMNA (0.42) LMNATSHRMEN1HPGDBLM
SCHEMBL107333 0.78 MGAM (0.38) LMNATDP1POLBALDH1A1GAA
SCHEMBL27690196 0.77 LMNA (0.31) LMNAPOLBALDH1A1
SCHEMBL8563170 0.76 ALDH1A1 (0.36) LMNATSHRPOLBALDH1A1GAA
SCHEMBL3470173 0.76
SCHEMBL13914924 0.76 LMNA (0.32) LMNAPOLB
SCHEMBL27742533 0.76 LMNA (0.32) LMNAHPGDBLMTDP1POLB
SCHEMBL991 0.76 TSHR (0.46) LMNATSHRMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530277-A Cationic photopolymerization type phosphate alicyclic epoxy monomer and preparation method and application thereof 北京化工大学 2024-08-23 CN claimed
CN-117447355-B Preparation method of milbelin intermediate 南京威凯尔生物医药科技有限公司 2024-03-19 CN claimed
WO-2018035249-A1 COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE AMINOCYCLOPROPANES IMAGO BIOSCIENCES, INC. (US) 2018-02-22 WO claimed
EP-2882030-B1 NON-AQUEOUS ELECTROLYTE AND ENERGY STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2017-06-21 EP claimed
EP-2698859-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND ELECTRICITY-STORAGE DEVICE USING THE SAME UBE INDUSTRIES (JP) 2016-07-27 EP claimed
EP-2581359-B1 REAGENT FOR TESTING PURIFICATION CAPACITY OF RADIOACTIVE GAS IN A NUCLEAR POWER PLANT, PREPARATION METHOD THEREOF AND IODIDE FILTER TESTING EQUIPMENT USING THIS REAGENT CHINA GENERAL NUCLEAR POWER (CN) 2016-03-30 EP claimed
EP-0719764-B1 3-Phenylisoquinolin-1(2H)-one derivatives as ligands of benzodiazepine receptors associated with GABAA receptors SYNTHELABO (FR) 1998-11-04 EP claimed
EP-0719776-B1 8-Oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoic acid derivatives as ligands of benzodiazepine receptors associated with GABAA receptors SYNTHELABO (FR) 1998-11-04 EP claimed
WO-1998000423-A1 1-OXO-1,2-DIHYDROISOQUINOLINE-4-PROPANAMIDE DERIVATIVES AND THEIR APPLICATION IN THERAPEUTICS SYNTHELABO (FR) 1998-01-08 WO claimed
US-5665733-A 3-phenylisoquinol-1(2H)-one derivatives their preparation and their therapeutic application SYNTHELABO (FR) 1997-09-09 US claimed
US-5614517-A TREATMENT OF NEUROLOGICAL DISORDERS INFLUENCED BY GAMMA-AMINOBUTYRIC ACID RECEPTORS SYNTHELABO (FR) 1997-03-25 US claimed
EP-0594940-B1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0719776-A1 8-Oxo-5,8-dihydro-6H-dibenzo(a,g) quinolizine-13-propanoic acid derivatives, their preparation and therapeutic use SYNTHELABO (FR) 1996-07-03 EP claimed
EP-0719764-A1 3-Phenylisoquinolin-1 (2H)-one derivatives as GABA receptor ligands SYNTHELABO (FR) 1996-07-03 EP claimed
EP-0594940-A1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed
US-5286741-A N-oxy- and thioalkylcarbonyloxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-02-15 US claimed
JP-7053484-A None JP disclosed
JP-8239383-A None JP disclosed
US-4151172-A Phosphonoacyl prolines and related compounds E. R. SQUIBB & SONS, INC. (US) 1979-04-24 US disclosed
EP-0000833-A1 Derivatives of phosphonoacyl prolines and their pharmaceutical use E.R. Squibb & Sons, Inc. (US) 1979-02-21 EP disclosed