Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007630 | 0.92 | PRSS1 (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL4006592 | 0.92 | ALDH1A1 (0.42) | THRATHRBALOX5PRSS1PRSS2 | |
| SCHEMBL9070058 | 0.86 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL5530602 | 0.86 | THRA (0.45) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL1100557 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL11674754 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL4009772 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL6849772 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL4004612 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 | |
| SCHEMBL39062 | 0.84 | THRA (0.59) | THRATHRBLIPGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208368-A | Reaction of diamine with phosgene in a solvent | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |